By chanhosong

PAINLESS GENE EXPRESSION PROFILING: SAGE (SERIAL ANALYSIS OF GENE EXPRESSION)

(August 2004) With the advent of the human genome project, a vast amount of information about genes and gene structure is suddenly at our fingertips. But this information is limited. Every cell within an organism has the same genetic composition (with the exception of its gametes), and yet, obviously skin tissue is very different from nervous tissue. The DNA sequence cannot provide information about these differences, which represent the next level of complexity and organization within an organism: DNA expression. Cells within a multicellular organism, such as ourselves, specialize to perform specific functions to increase the efficiency of the organism.…