By Amanda Dancsok, Yuda Shih, and David Twa

Amanda Dancsok is a Saskatchewan-born MD/PhD student at UBC studying experimental therapeutics for rare soft tissue cancers. Yuda Shih is a second year Master's student in the Department of Pathology and Laboratory Medicine. His research interests include signaling mechanisms that promote myelination in the central nervous system. Dave enjoys passaging cells, filling out graduate fellowship applications that he has a statistically significant (P<0.05) probability of not winning, troubleshooting, troubleshooting and troubleshooting. Every third full moon from 11:00-11:16pm, he very occasionally engages in something which might resemble research, but only if Mars lines up with one of Jupiter’s moons and the tide is out.

IDENTIFICATION OF HUMAN CHROMOSOME γ AND ITS EPIGENETIC CONTROL FOR THE EXPRESSION OF “SUPER” GENES

– – – New England Journal of Medicine. (March 2013). Vol 328 No 12. DOI: 10.1738/NEJMoal219833 – pdf download ABSTRACT BACKGROUND Superheroes possess exceptional characteristics that far exceed the scope of human capabilities, such as the tremendous strength and pigmentation observed in The Incredible Hulk following his exposure to γ-radiation. Here, we explore the underlying molecular mechanisms for the “superhuman” abilities seen in the Hulk, as compared to semi-superheroes Papa Smurf and Popeye the Sailor. In particular, we examine the role of epigenetic mechanisms, principally DNA methylation, in the genotypic expression of “super” genes and their phenotypic manifestation. METHODS Whole…