From journal club

MUTATIONS IN THE SEED REGION OF WIZARD mIR-96 ARE RESPONSIBLE FOR HEREDITARY PARSELTONGUE HYPERACUSIS

Annals of Praetachoral Mechanics (2016). Vol 2. Advanced online publication. download pdf ABSTRACT Parseltongue is a rare hereditary trait that allows wizards to communicate in the language of serpents. Wizards who are parseltongue not only have the ability to speak to serpents (parselmouth), but also possess the ability to hear ultrasonic frequencies produced by the snake (parseltongue hyperacusis). Genome wide association studies (GWAS) have identified scores of genetic variants that contribute to different wizarding phenomenon. MicroRNAs negatively regulate mRNA expression by binding complementary sites in target mRNAs, with the specificity of interaction being crucially dependent on the miRNA seed region.…

WHY SOME PEOPLE MAKE THE WRONG DECISION AND OTHERS DON’T: AN ASSESSMENT OF ARITHMETIC AND GEOMETRIC PROJECTIONS OF THE FRIDAY-SUNDAY DIVIDE BEYOND THE MEHSPAIR CHASM WITH P-VALUES, χ2, AND LICORICE

ABSTRACT So it’s come to this. Another year has passed and another Candy Hierarchy survey has been completed. Check that. “Candy Hierarchy” is what yahoos call it, but to us, it’s a deep dive into the Friday/Sunday question that has blessed our species since caveman times. Caveman times. We’ve taken a look at the data, and frankly, we don’t like what we see. Maybe it’s not all bad. Maybe. Let’s start with the good. Remember last year when a couple of plucky scientists who had overcome obscure forms of childhood adversity before finding their footing in a ne’er do well…

2016 CANDY HIERARCHY: SUPPLEMENTAL RAW DATA AND NEW ANALYSES

PREAMBLE: This is for you data nerds who might want to dig into the data a little deeper (we didn’t have a lot of time to play around with it). We’ve provided access to the full excel spreadsheet (which also includes data that was cut off from our analysis due to us having to get started earlier for today’s piece on BoingBoing). We’re essentially hoping that with more rigorous analysis of the data, we might be able to find out whether there are statistically relevant differences in how different folks rate their candies For example, do people who see the…

NucSh REGULATES NECESSARY NUCLEIC SHRINKAGE FOR GENOME SWAP IN POLYJUICE POTION

Annals of Praetachoral Mechanics (2016). Vol 2. Advanced online publication. download pdf ABSTRACT This study provides further investigations into the wizarding potion known commonly as the Polyjuice potion; and specifically to assess the contribution of the known fluxweed protein, NucSh. NucSh has been previously shown, via co-immunoprecipitation experiments, to be part of the PhageCrux Complex, which in turn appears to be key for many major transformative magic related properties. Other studies have also shown that the principle factor of this Auror favorite is possibly related to a symbiotically absorbed and retained bacteriophage present in Lacewing flies (Borage et al, 2009).…

IDENTIFICATION AND LOCALIZATION OF THE SANEW GENE IN MAGICAL WOLFSBANE (ACONITUM ALUPUS)

Annals of Praetachoral Mechanics (2016). Vol 2. Advanced online publication. download pdf ABSTRACT For more than 100 years, those suffering from werewolfism have relied on the Wolfsbane Potion to maintain cognitive abilities during transformation. Recent developments in biotechnology and biochemistry have allowed for in-depth study of the chemistry and genetics of magical plants such as Aconitum alupus, the most important herbal component of Wolfsbane Potion. A recent study identified mesaconitine as the potion-active metabolite of A. alupus, though the details of its biosynthesis have not yet been elucidated. In this paper we reported the discovery of the gene SANEW which…

EXPRESSION OF MaGc77 IS A SPECIFIC AND SENSITIVE MARKER FOR THE PATRONUS (Pt) CHROMOSOME (MGR-ABL1) TRANSLOCATION IN INHERITED MAGICAL ABILITIES

Annals of Praetachoral Mechanics (2016). Vol 2. Advanced online publication. download pdf ABSTRACT Magical abilities have been estimated to occur in about 17% of the human population. However, the cause of discrepancy between wizards/witches and muggles (non-magical humans) remains largely unknown. More surprisingly, the presence of squibs (individuals with no magical abilities despite a magical heritage) and muggle-born wizards and witches indicates a genetic component to magical abilities, which has yet to be understood. Recently, the MaGc77 protein was described as playing a potential role in the conference of magical abilities in individuals. Here we describe the underlying genetic event…

STRATIGRAPHICAL ANALYSIS OF FRIDAY-SUNDAY IDENTIFICATION IN RELATION TO SUGAR CONSUMPTION PREFERENCES AND RELATED DEMOGRAPHIC VARIABLES

Advanced online publication. Download pdf. *Data Analysis report for the 2015 Candy Hierarchy (raw data | source reference) ABSTRACT The 2015 Candy Hierarchy defines the quality ranking of all known candies (minus those that were not ranked). It’s really easy to analyze too. We did it. Here are the results. They reveal a natural law of those who identify as Friday people and Sunday people, which holds across time and space at a stable 2-to-1 ratio or, 66/33, or, .5/.25 depending on how many characters are left In your tweet. It confirms that Friday people are better. Suck it Sunday.…

WZRD1 GENE, A POSSIBLE MARKER FOR SQUIBIDITY DISORDER IN HOMO SAPIENS

Annals of Praetachoral Mechanics (2016). Vol 2. Advanced online publication. download pdf ABSTRACT From the limited number of studies previously done on Squibidity, there is great potential for advancements that would further our understanding of this disorder, and which would benefit both magical and non-magical people. Squibidity, is one of the most mysterious conditions to affect the Wizarding world. It is estimated that approximately 1 out of every 1200 individuals, who are born into a Wizarding family, are affected. The severity of this condition varies, but most individuals with this phenotype lack the ability to perform magic of any kind,…