By jiyuan

GENETIC STUDIES OF AGING AND LONGEVITY IN MODEL ORGANISMS

(August 2004) Aging can be characterized as: (1) an inevitable consequence of being a multicellular organism; (2) associated with a random, passive decline in function; (3) leading to a global loss of homeostasis (the state of sustained equilibrium in which all cells, and all life forms, exist) over time; and (4) mortality increasing with age [1]. Age is not a disease, but it does predispose an organism to a variety of diseases [2], in the case of humans, this includes heart disease, arthritis, osteoporosis, diabetes, cancer and Alzheimer’s. Achieving longevity is thought to be caused by a combination of factors.…