(August 2004) It has been 15 years now that the Cre/lox system has been used as a way to artificially control gene expression. If your radar hasn’t picked it up yet, you’re missing out on a clever way to move pieces of DNA around in a cell. Over the years, this system has allowed researchers to create a variety of genetically modified animals and plants with the gene of their choice being externally regulated [1]. This has contributed to our understanding of how individual genes and proteins work. How it works The system begins with the cre gene, short for…